Shaoling Li,Manshiu Leung,Hao Zhang,Venkat R. Thalladi,Yun Mo
申请号:
US16454353
公开号:
US20190321350A1
申请日:
2019.06.27
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention provides a solid composition of the peripheral mu opioid antagonist axelopran and a combination dosage form of the mu opioid antagonist axelopran sulfate in an immediate release form and an opioid analgesic agent which may be in an extended release, sustained release, modified release, or controlled release form and methods of preparing such a combination dosage form.