A patient-specific knee implant 10 includes a femoral component 20 and a tibial tray component 30, and it is designed based on patient-specific data. An inner, bone-facing surface 40 of the femoral component 20 conforms to the corresponding surface of the femoral condyle. Alternatively, it can conform to one or more optimized bone cuts on the femoral condyle. However, the outer, articular surface 50 of the component 20 is enhanced to incorporate a smooth surface having a nearly constant radius in the coronal plane. The corresponding articular surface 70 of the tibial tray 30 has a surface contour in the coronal plane that is matched to the outer articular surface 50. In certain embodiments, the articular surface 50 of the component 20 incorporates a sagittal curvature that positively-matches the patient's existing or healthy sagittal radius.