A fluid management system adapted to automatically supply fluid for injection into a patient is disclosed. The fluid management system includes a fluid management device, a fluid transfer system and a fluid injector. The fluid management device serves to store and administrate multi-dose containers. The fluid transfer system connects an outlet of these containers to the injector which withdraws a fluid from the containers via the fluid transfer system and injects the fluid to an administration device at the patient. The fluid management device includes at least one rotating carousel having a vertical axis of rotation, at least two container holders attached to the rotating carousel and adapted to position the container vertically with a septum covered end facing downwards, and a spike holder mounted below the rotating carousel and oriented so the spike holder axially aligns a spike connected to the spike holder with the axis of the container.