LINDNER, JONATHAN, R.,KAUFMANN, BEAT,MCCARTY, OWEN, J., T.
申请号:
EP08746265
公开号:
EP2148662A4
申请日:
2008.04.18
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Compositions and methods for detecting various disorders with targeted microbubbles are disclosed. Specifically, microbubbles comprising glycoprotein Ib (GPIb), ligands for VCAM- 1, and ligands for P-selectin such as PSGL-1 are disclosed. Also disclosed are methods for using targeted microbubbles to detect cardiovascular disease comprising administering the disclosed microbubbles to a subject and detecting the microbubbles in the vasculature using ultrasound.Linvention concerne des compositions et des procédés pour détecter divers troubles avec des microbulles ciblées.