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Cholesterol derivatives of inhibitors of viral fusion
专利权人:
Antonello Pessi;Paolo Ingallinella;Elisabetta Bianchi
发明人:
Antonello Pessi,Elisabetta Bianchi,Paolo Ingallinella
申请号:
US12738998
公开号:
US08629101B2
申请日:
2008.10.20
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to compounds comprising at least ten contigous amino acids of the HR2 domain of a Type 1 viral fusogenic protein of an enveloped virus, or a derivative thereof, attached at the C-terminal to cholesterol or a derivative thereof; or a pharmaceutically acceptable salt thereof which inhibit viral fusion. Thus compounds of the invention are useful to prevent or treat diseases caused by an enveloped virus.
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