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Methods of in vitro oocyte development
专利权人:
The University Court of the University of Edinburgh
发明人:
Evelyn Elizabeth Telfer,Marie McLaughlin
申请号:
US15513628
公开号:
US10655101B2
申请日:
2015.09.24
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Methods of preparing ovarian tissue for primordial follicle growth are presented comprising the steps: providing an ovarian tissue sample comprising cortical tissue and stromal tissue; removing damaged tissue from the ovarian tissue sample where present; removing excess stromal tissue from the ovarian tissue sample where present; and then mechanically stretching the ovarian tissue sample along at least one dimension of the ovarian tissue sample, such that the size of the ovarian tissue sample along the at least one dimension is increased by at least 10%. Methods of growing viable oocyte in vitro, and methods of preparing individual ovarian follicles for growth are also presented.
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