The present paper describes peptide vaccines against cancer. In particular, it provides isolated Peptide epitopes derived from (2 kntc2 kinetochore Associated gene (LTC) that cause Cytotoxic T Lymphocyte) and are therefore suitable for use in the context of the Immunotherapy of cancer.The peptides of the present cover both peptides derived from kntc2 as modified versions of the same, in which one, two or several amino acids are replaced, deleted, inserted or Aggregates, provided that these modified versions retain the inducibility of LTC necessary L The original sequences.Furthermore provides polynucleotides encoding these peptides and Pharmaceutical compositions that include any of these peptides and polynucleotides as active agents. Also provided are Antigen Presenting cells and isolated LTC for these Peptides, as well as methods to induce host Cell Antigen or LTC.In addition, this provides methods for the treatment and / or prophylaxis (i.e., Prevention of Cancer (tumor) and / or the Prevention of the postoperative recurrence or metastasis of the same, and Methods for Inducing LTC, Methods for Inducing Immunity antitumorosa, using Peptides derived from kntc2,Polynucleotides encoding peptides or Antigen Presenting cells with peptides and Pharmaceutical compositions of the present.En el presente documento se describen vacunas de péptidos contra el cáncer. En particular, se proporcionan péptidos epítopos aislados derivados del gen KNTC2 (cinetocoro asociado 2) que provocan LTC (linfocito T citotóxico) y por lo tanto son convenientes para el uso en el contexto de la inmunoterapia del cáncer. Los péptidos de la presente abarcan tanto péptidos derivados de KNTC2 como versiones modificadas de los mismos, en las cuales uno, dos o varios aminoácidos son sustituidos, suprimidos, insertados o agregados, siempre que estas versiones modificadas retengan la inducibilidad de LTC necesaria de las secuencias originales. Además se proporcionan polinucleótidos que codifican estos
