#$%^&*AU2011205030B220150507.pdf#####15 ABSTRACT The present invention provides an animal caging system 10 including at least one substantially air-tight cage 14 having a top 92, the cage 14 including an air intake port 94 and an air exhaust port 121, the air exhaust port 121 being located at said top 92 of said cage 14; and a rack 12 having a rack frame 24, 28 and at least one shelf 36 supported on said rack frame, said rack frame having at least one air exhaust plenum 70. The cage 14 and a portion of the rack 12 are adapted to form a chamber therebetween when said cage 14 is mounted underneath of said shelf 36, said chamber having a first opening 71 and a second opening 113, said first opening 71 communicating with said air exhaust plenum 70, said second opening 113 communicating with said air exhaust port 121 of said cage 14 to permit air to be drawn into said air exhaust plenum from the interior of said cage 14.1/18 U -P 00