CHALLITA-EID, PIA M.,FARIS, MARY,RAITANO, ARTHUR B.,JAKOBOVITS, AYA,GE, WANGMAO
申请号：
CA2493928
公开号：
CA2493928C
申请日:
2003.08.15
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
A novel gene 273P487 and its encoded protein, and variants thereof, aredescribed wherein 273P487 exhibits tissue specific expression in normal adulttissue, and is aberrantly expressed in the cancers listed in Table I.Consequently, 273P4B7 provides a diagnostic, prognostic, prophylactic and/ortherapeutic target for cancer. The 273P487 gene or fragment thereof, or itsencoded protein, or variants thereof, or a fragment thereof, can be used toelicit a humoral or cellular immune response； antibodies or T cells reactivewith 273P4B7 can be used in active or passive immunization.
