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USE OF SKIN PENETRATION ENHANCERS AND BARRIER DISRUPTION AGENTS TO ENHANCE THE TRANSCUTANEOUS IMMUNE RESPONSE INDUCED BY ADP-RIBOSYLATING EXOTOXIN
专利权人:
THE GOVERNMENT OF THE UNITED STATES; AS REPRESENTED BY THE SECRETARY OF THE ARMY
发明人:
GLENN, GREGORY M.,ALVING, CARL R.
申请号:
CA2321596
公开号:
CA2321596C
申请日:
1999.02.25
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
A transcutaneous immunization system where the topical application of anadjuvant and an antigen or nucleic acid encoding for an antigen, to intactskin induces a systemic or mucosal antibody response. The immune response soelicited can be enhanced by physical or chemical skin penetration enhancement.
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