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PRINCIPE ACTIF CRISTALLIN SÉCHÉ PAR PULVÉRISATION
专利权人:
FIRMENICH S.A.
发明人:
申请号:
EP11716063.0
公开号:
EP2552234B1
申请日:
2011.03.28
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
A process for preparing a spray-dried product for improving the rate of dissolution of the active ingredient. The process includes mixing a crystalline active ingredient, which has a dissolution rate in unstirred water at 25° C. of greater than 15 minutes at a concentration of 14 ppm of the active ingredient, with a starch derivative, a second carrier material, and optionally, xanthan gum, to form a suspension, dispersion or solution of the active ingredient; homogenizing the mixture at a pressure of at least 4000 psig (2.758×107 Pa); and spray-drying the homogenized mixture to provide a spray-dried active ingredient that has an increased dissolution rate in water compared to the unencapsulated active ingredient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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