Kapp, Gregory,Serwer, Laura,Le Moan, Natacha,Cary, Stephen P.L.
申请号:
AU2013204158
公开号:
AU2013204158A1
申请日:
2013.01.07
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2013204158A120140724.pdf#####POLYMERIC FORMS OF H-NOX POTEINS ABSTRACT The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of HNOX proteins as radiosensitizers for the treatment of brain cancers. 135