Methods for guiding a patient or a caregiver thereof along a medical trajectory associated with a medical problem of the patient include: (a) displaying, by a processor, at least one designating query to the patient and/or the caregiver, the at least one designating query designed to ascertain a severity level of a first biomarker associated with the medical problem； (b) receiving a response from the patient and/or the caregiver to the at least one designating query； (c) correlating the response to the at least one designating query with a severity level of the first biomarker； and (d) displaying a designated severity level of the first biomarker in a graphical format. Systems for guiding a patient or a caregiver thereof along a medical trajectory associated with a medical problem of the patient are described.
