ROBINSON MICHAEL R.,BLANDA WENDY M.,HUGHES PATRICK M.,RUIZ GUADALUPE,ORILLA WERHNER C.,WHITCUP SCOTT M.,LIN JOAN-EN,WELTY DEVIN F.,SPADA LON T.
申请号：
NZ60092107
公开号：
NZ600921A
申请日:
2007.11.09
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a biocompatible, injectable intraocular drug delivery system comprising: (a) a plurality of microspheres with an average diameter between about 8 microns and about 14 microns, and (b) an aqueous vehicle for the microspheres, wherein the microspheres consist essentially of: (1) a therapeutic agent which is estradiol or 2-methoxyestradiol, and (2) one or more biodegradable polymers, all of which biodegradable polymers are polylactic acid (PLA) polymers, and wherein the drug delivery system has a viscosity which permits the drug delivery system to be injected into an intraocular location through a 20 to 30 gauge syringe needle.
