MACNEVIN, CHRISTOPHER,STEIN, DONALD G.,LIOTTA, DENNIS C.,SAYEED, IQBAL,GUTHRIE, DAVID B.,LOCKWOOD, MARK A.,NATCHUS, MICHAEL G.
申请号:
CA2716095
公开号:
CA2716095C
申请日:
2009.02.26
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Provided are steroid analogues functionalized with polar substituents at theC3 and/or C20 positions of the steroidring system that exhibit improved water solubility. Also provided arepharmaceutical compositions comprising the steroidana-logues and methods using the novel steroid analogues for the treatment andprevention of neurodegeneration in a patient followinginjury to the central nervous system.