A catheter hub includes a hub body defining a first lumen and a second lumen. At least a portion of the first lumen defines a first longitudinal axis, and at least a portion of the second lumen defines a second longitudinal axis. A cap coupled to the hub body is configured and arranged in a non-intersecting orientation relative to the first and second longitudinal axes. A first arm and a second arm each includes a distal portion coupled to the hub body, and a proximal portion which is movable, in a direction toward a respective longitudinal axis, into releasable engagement with the cap.