FERRO, VITO,FAIRWEATHER, JON KRUEGER,KAROLI, TOMISLAV,LIU, LIGONG
申请号:
CA2557989
公开号:
CA2557989C
申请日:
2005.03.04
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The invention relates to compounds which are polysufated oligosaccharidederivatives having activity as inhibitors of heparan sulfate-binding proteinsand inhibitors of the enzyme heparanase; methods for the preparation of thecompounds; compositions comprising the compounds, and use of the compounds andcompositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment,lowering of blood triglyceride levels and inhibition of cardiovascular diseaseof a mammalian subject.