The present invention relates a pharmaceutical composition for the treatment of proliferative diseases, such as tumor, wherein the pharmaceutical composition contains a compound of formula (I) or its pharmaceutically acceptable salts and at least one antiproliferative medicament. The pharmaceutical combination has a synergistically increased action.本發明涉及一種用於治療增生性疾病如腫瘤的醫藥組合物,其中含有式I化合物或其可藥用鹽,以及至少一種抗增生劑。所述的藥物組合形式具有協同增效作用。