This invention relates to a device (10) for taking at least one sample of soft tissue from an organ, said device comprising a body (11) and a needle (12) formed by a stylet (13) and a cannula (14) coaxial with said stylet, said device comprising a mechanism for arming the needle, designed for sequentially moving the cannula (14) and then the stylet (13) from a rest position wherein the stylet and the cannula are extended towards the outside of the body, to a shooting position wherein the stylet and the cannula are retracted towards the rear of the body, and a triggering mechanism designed to release the stylet then the cannula and to allow their displacement from the shooting position to the rest position, the cannula being coupled kinematically to a cannula slider (24) comprising at least one retaining element (26) for maintaining the cannula slider in a shooting position, the stylet being coupled kinematically to a stylet slider (30) comprising at least one retaining element (32) for maintaining the stylet slider in a shooting position and means for unlocking (34) the cannula slider. At least one of said retaining elements of the cannula slider (26) or stylet slider (32) comprises at least a hook (50) arranged to rest against a corresponding retaining element (27, 33) in a locking position and to release the retaining element (27, 33) in a shooting position. The retaining element is unhooked from said retaining means by a striker (51), this striker comprising elastic blades (52) which number is at least equal to the number of hooks of said retaining element, these elastic blades (52) being arranged to be in contact with said hooks. The striker (51) cooperates with a stressing ring (53) arranged around the elastic blades (52) of the striker (51), this stressing ring (53) being arranged to be movable in a first stressing position, in which said ring acts on the elastic blades (52) of the striker and forces them in order to allow a sufficient force to be applied to t
