The present specification describes systems for connecting/disconnecting a main connector of an endoscope assembly to the main control unit. In an embodiment, the system includes an elongated protruding member located on the main connector which is adapted to fit into a female fitting member placed in an opening on the surface of the main control unit wherein said female fitting member is coupled to a motor, which on activation causes the female fitting member to rotate and engage with the elongated protruding member. In an embodiment, the system includes a male bayonet component located on the main connector for connecting with a female bayonet component placed in an opening on a surface of the main control unit, wherein said female fitting member is coupled to a slidable switch through a crankshaft in the main control unit.