A surgical instrument is provided with a gripping part arranged in a stationary manner on a tubular guide housing having a guide hole and with an actuating lever, which is pivotably mounted thereon and which is in functional connection via a lever arm with a plunger. The plunger is axially shiftable in a mounting housing, via which a tool can be actuated. The plunger has, in its end area located adjacent to the lever arm, a circumferential, radially expanded pushbutton, via which the plunger is guided axially adjustably against the spring force of an axial compression spring in the guide hole of the guide housing. The mounting housing is provided with a ring shoulder for axial fixation in the guide hole of the guide housing.
