Genetic engineering of non-human animals for the production of chimeric antibodies

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专利权人:

Ablexis LLC

发明人:

Green, Larry,Shizuya, Hiroaki

申请号：

AU2011234988

公开号：

AU2011234988B2

申请日:

2011.03.31

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The invention provides non-human cells and mammals having a genome encoding chimeric antibodies and methods of producing transgenic cells and mammals. Certain aspects of the invention include chimeric antibodies, humanized antibodies, pharmaceutical compositions and kits. Certain aspects of the invention also relate to diagnostic and treatment methods using the antibodies of the invention.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/