Petra Marcella Francoise Blom,Jan Marie Cyriel Jozef Hoflack,Pascal Andre Rene Benderitter
申请号:
US14776798
公开号:
US09586975B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to macrocyclic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of SIK kinase, more in particular SIK1, SIK2 and/or SIK3 and/or mutants thereof, for use in the diagnosis, prevention and/or treatment of SIK-kinase associated diseases. Moreover, the present invention provides methods of using said compounds, for instance as a medicine or diagnostic agent.