Provided are compositions containing a conjugate containing a phthalocyanine dye, including compositions containing stabilizing agents, such as non-ionic surfactants and/or protectants. In some aspects, the compositions result reduced aggregation of the conjugate due to agitation, temperature exposure, and/or pH. Also provided are articles of manufacture containing the compositions containing the conjugates, and methods for their administration to subjects for photoimmunotherapy. In some embodiments, the phthalocyanine dye conjugates are conjugated to a targeting molecule, such as an antibody, that targets the conjugate to a cell or pathogen, such as by binding to a cell surface protein.本發明提供含有酞菁染料之結合物的組合物，包括含有穩定劑(諸如非離子表面活性劑及/或保護劑)之組合物。在一些態樣中，該等組合物由於攪動、溫度暴露及/或pH造成該結合物之聚集減少。亦提供含有該等結合物之組合物的製品，及將其投與個體用於光免疫療法之方法。在一些實施例中，該等酞菁染料結合物結合至靶向分子，例如抗體，例如藉由結合至細胞表面蛋白將該結合物靶向細胞或病原體。
