The purpose of the invention is to develop an improved device for injecting pulsed steam into a human or animal vessel (e.g. veins), especially tributaries and perforating veins to treat them through thermofibrosis. The device of the invention includes a water pulse generator that produces micro pulses of pressurized sterile water a hand piece that transforms pulses of water coming from the generator into pulses of steam an endoluminal catheter with a tubular part for delivering the steam into the vessel connection means between the hand piece and the endoluminal catheter and a programmable central processing unit (cpu) to control the water pulse generator and the hand piece.