TECHNICAL UNIVERSITY OF DENMARK;NANOVI RADIOTHERAPY APS
发明人:
Thomas Lars Andresen,Rasmus Irming Jølck,Linda Maria Bruun
申请号:
US16302517
公开号:
US20190275174A1
申请日:
2017.05.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to a palpable marker composition comprising non-water soluble carbohydrates, wherein at least 50% of the non-water soluble carbohydrates are carbohydrates selected from derivatives of lactose, maltose, trehalose, raffinose, glucosamine, galactosamine, lactosamine, or derivatives of disaccharides with at least two pyranose saccharide units, trisaccharides, tetrasaccharides, or mixtures thereof, and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 50,000 centipoise (cP) after administration, for use for identifying and/or locating a non palpable tumor. In one embodiment the composition the composition is a liquid before administration into the human or animal body that increases in viscosity by more than 500,000 centipoise (cP) after administration into the human or animal body. In another embodiment the composition is a liquid before administration and has the ability to transform into a crystalline or amorphous solid after administration.