An adjustable orthostatic intolerance garment formed of a knitted spandex powernet construction in order to provide compression when on the leg, and including legs and a torso portion that extends upwardly into the abdominal area below the pectoral muscles; and a respective pair of elongate panels that are retained in place by attaching elements, and that are introduced into or removed from the garment to increase or reduce compression on the wearer's body as desired.