AN IMPROVED PROCESS FOR THE PREPARATION OF SUNITINIB AND ITS ACID ADDITION SALTS THEREOF

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专利权人:

Laurus Labs Limited

发明人:

申请号：

EP13763825.0

公开号：

EP2828251B1

申请日:

2013.03.22

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention relates to a kind of improved preparation Sunitinb. This method is related in activation Z 5- (()-(5-fluoro-2- oxoindolin-3-ylidene) methyl) -2,4- methyl-1 H-pyrrole-3carboxylic acid to corresponding suitable carboxylic acid activating group. The present invention also relates in novel acid addition salt Sunitinb and its preparation.

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中国工程科技知识中心

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http://www.ckcest.cn/home/