Device for cutting and aspiration of tissue from human or animal body, in particular for use in vitrectomy for peeling of the retina, with an outer tube (1) and a concentrically movable inner tube (5) and so Alternatively, with a little play, in the outer tube (1), the outer tube (1) at the free end being closed and having near the free end (2) a side hole (3) with at least one edge of the inner cutting (6), the inner tube (5) at the free end (2) being open and presenting here an edge outer cutting (6), and interacting cutting edges (4, 6) during movement of the inner tube (5 ) to produce the cut, wherein the inner tube (5), near the free end, (2) at least one lateral opening (7) with at least another edge of outer cutting (8), characterized in that the holes (3, 7) and thus the cutting edges (4, 6, 8) of the tubes (1, 5) are arranged relative to one another last like all development movement of the inner tube (5) so that the holes (3, 7) are dimensioned such and the movement of the inner tube (5) is limited so that, at any time of development motion is present the same cross section of flow into the inner tube (5).Dispositivo para el corte y la aspiración de tejido del cuerpo humano o animal, en particular para su uso en la vitrectomía, para el peeling de la retina, con un tubo exterior (1) y un tubo interior (5) desplazable concéntricamente y de manera alterna, con un pequeño juego, en el tubo exterior (1), estando cerrado el tubo exterior (1) en el extremo libre y presentando cerca del extremo libre (2) un orificio lateral (3) con al menos una arista de corte interior (6), estando abierto el tubo interior (5) en el extremo libre (2) y presentando aquí una arista de corte exterior (6), e interactuando las aristas de corte (4, 6) durante el desplazamiento del tubo interior (5) para producir el corte, presentando el tubo interior (5), cerca del extremo libre, (2) al menos un orificio lateral (7) con al menos otra arista de corte exterior (8), caracterizado por que l