University of Pittsburgh- Of the Commonwealth System of Higher Education
发明人:
BADYLAK, Stephen, F.,KEANE, Timothy, Joseph, Jr.,WHITE, Lisa, Jane
申请号：
EP16847449
公开号：
EP3349814A1
申请日:
2016.09.16
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Provided are methods for preparing non-gelling, solubilized extracellular matrix (ECM) materials useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the non-gelling, solubilized ECM composition is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient. In another embodiment, the composition is delivered intraarticularly, intrathecally, intraoccularly, intracranially, and into pleural space.
