RISER, BRUCE L.,WHITE, JEFFREY A.,DALTON, CHRISTOPHER R.
申请号:
CA2797138
公开号:
CA2797138C
申请日:
2011.04.22
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Methods and compositions for reducing, preventing or reducing the progression of calcification in peritoneal dialysis patients are provided. In an embodiment, the present disclosure provides a method comprising administering to a patient during peritoneal dialysis therapy a dialysis solution comprising a therapeutically effective amount of pyrophosphate ranging between about 30 µM and about 400 µM. Formulations of dialysis solutions according to the dose ranges claimed in the present disclosure allow therapeutic amounts of pyrophosphate to be delivered to peritoneal dialysis patients.