Guangzhou Institute Of Biomedicine And Health; Chinese Academy Of Sciences
发明人:
申请号:
EP18877609.0
公开号:
EP3712260A1
申请日:
2018.11.13
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Provided is a genetically engineered γδT cell, which is characterized in that a high-affinity αβTCR gene is transferred into the γδT cell, and the affinity of the high-affinity αβTCR to the specific pMHC thereof is at least two times of that of a wild-type αβTCR corresponding thereto. Further provided are a use of and a preparation method for the γδT cell.