MODULATEUR DE REGULATEUR DE CONDUCTANCE TRANSMEMBRANAIRE DE FIBROSE KYSTIQUE, COMPOSITIONS PHARMACEUTIQUES, PROCEDES DE TRAITEMENT ET PROCEDE DE FABRICATION DU MODULATEUR
ABELA, ALEXANDER RUSSELL,ALCACIO, TIMOTHY,ANDERSON, COREY,ANGELL, PAUL TIMOTHY,BAEK, MINSON,CLEMENS, JEREMY J.,CLEVELAND, THOMAS,FERRIS, LORI ANN,GROOTENHUIS, PETER DIEDERIK JAN,GROSS, RAYMOND STANLEY
申请号:
CA3046086
公开号:
CA3046086A1
申请日:
2017.12.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Compounds of Formula (I) pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.