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Antifungal compositions with improved bioavailability
专利权人:
发明人:
Lieven E. C. Baert,Geert Verreck,Dany Thone
申请号:
US14069842
公开号:
US09642806B2
申请日:
2013.11.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.
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