MCMINN, DUSTIN,JOHNSON, HENRY,BOWERS, SIMEON,MOEBIUS, DAVID C.
申请号：
PE0019162015
公开号：
PE15582015A1
申请日:
2014.03.14
申请国别(地区):
PE
年份:
2015
代理人:
摘要：
Refers to compounds tripeptidicos epoxy ketone of formula (X) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, K, e, M, N, P and q are as defined in the description. It also relates to a Pharmaceutical composition. These compounds are useful as protease inhibitors in the treatment of autoimmune diseases and Neurodegenerative DiseasesSE REFIERE A COMPUESTOS TRIPEPTIDICOS DE EPOXI CETONA DE FORMULA (X) Y SALES FARMACEUTICAMENTE ACEPTABLES, DONDE R1, R2, R3, R4, K, E, m, n, p Y q SON COMO SE DEFINEN EN LA DESCRIPCION. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE PROTEASA SIENDO UTILES EN EL TRATAMIENTO DE ENFERMEDADES AUTOINMUNES Y ENFERMEDADES NEURODEGENERATIVAS
