MOLÉCULA DE LIGAÇÃO AO ANTIGÉNIO CAPAZ DE SE LIGAR REPETIDAMENTE A DUAS OU MAIS MOLÉCULAS DE ANTIGÉNIO

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专利权人:

CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

SHINYA ISHII,ATSUHIKO MAEDA,TOMOYUKI IGAWA,TAKASHI NAKAI

申请号：

PT13195718

公开号：

PT2708559T

申请日:

2009.04.10

申请国别(地区):

PT

年份:

2018

代理人:

摘要：

The present inventors discovered that antibodies having weaker antigen-binding activity at the early endosomal pH in comparison with that at the pH of plasma are capable of binding to multiple antigen molecules with a single antibody molecule, have long half-lives in plasma, and have improved durations of time in which they can bind to antigen.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/