Colorado State University Research Foundation;Calimmune, Inc.;The University of North Carolina at Chapel Hill
发明人:
GOODRICH, Laurie, R.,MCILWRAITH, C. Wayne,BARTLETT, Jeffrey, S.,SAMULSKI, Richard, Jude
申请号：
EP17842198
公开号：
EP3503928A4
申请日:
2017.08.18
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Methods and compositions for treating symptoms of conditions such as but not limited to osteoarthritis in horses. The methods may feature direct intraarticular injection of a recombinant self-complementary adeno-associated virus (sc-rAAV) with a vector adapted to express a modified IL-1 Ra peptide. The methods of the present invention may express a therapeutically effective amount of the modified IL- 1 Ra peptide so as to ameliorating symptoms associated with the condition being treated.
