An instrument for an endoscope includes an insertion portion inserted into an instrument insertion channel of the endoscope, and a pair of biopsy cups provided at the distal end of the insertion portion so as to be able to be openable and closable. Also, an operation portion for operating the paired biopsy cups is provided at the proximal end of the insertion portion. The operation portion is provided with a hook, and an engaged member engageable with the hook is attached to a part protruding out from the endoscope, of the insertion portion.