光学活性イソキサゾリン化合物の触媒的不斉合成方法及び光学活性イソキサゾリン化合物

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专利权人:

日産化学工業株式会社

发明人:

外山 賢一,森山 祐二,的場 一隆,八尾坂 学,池田 栄達

申请号：

JP20130543024

公开号：

JP6075563(B2)

申请日:

2012.11.08

申请国别(地区):

日本

年份:

2017

代理人:

摘要：

There is provided a method for catalytic asymmetric synthesis of optically active isoxazoline compound and an optically active isoxazoline compound. A method for catalytic asymmetric synthesis of optically active isoxazoline compound of a formula (6) including reacting an α,&bgr;-unsaturated carbonyl compound of a formula (1) and a hydroxylamine in a solvent in the presence of a base by adding a chiral phase transfer catalyst. An optically active isoxazoline compound of a formula (13) that can be synthesized by the method.

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