Anti-PD-1/anti-VEGF natural antibody structure-like heterodimeric form bispecific antibody and preparation thereof

• 收藏
• 分享

专利权人:

Beijing Hanmi Pharmaceutical Co.; Ltd.

发明人:

YANG, Yaping,SONG, Nanmeng,XIAO, Wenchu,LI, Zhenlei,ZHANG, Lina,GU, Mingyue,ZHAN, Chunguang,LIU, Jiawang,KIM, Maengsup

申请号：

AU2019218433

公开号：

AU2019218433A1

申请日:

2019.02.02

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

An anti-PD-1/anti-VEGF natural antibody structure-like heterodimeric form bispecific antibody and the preparation thereof. Provided are a highly stable, heterodimeric form anti-PD-1/anti-VEGF bispecific antibody having natural IgG characteristics and free of mismatched heavy and light chains and a preparation method for the antibody. The bispecific antibody is capable of simultaneously binding with two target molecules and provides improved efficacy in treating a complicated disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/