GONCHAR NATALJA VASILEVNA,Гончар Наталья Васильевна,ALEKHINA LJUDMILA ALEKSEEVNA,Алехина Людмила Алексеевна,SUVOROV ALEKSANDR NIKOLAEVICH,Суворов Александр Николаевич,GRIGOREV STEPAN GRIGOREVICH,Григо
申请号:
RU2012141867/15
公开号:
RU0002502995C1
申请日:
2012.10.01
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
FIELD: medicine.SUBSTANCE: disadvantages of the known methods are the absence of usage data in premature infants, including for the purpose of prevention, as well as a low accuracy degree. What is presented is predicting a success rate of the prevention of any infectious complications in premature newborns in the period of hospital nursing by taking into consideration the perinatal history, clinical-laboratory data, and by prescribing a probiotic. The above probiotic is a liguid form of E. faecium L3 the values of linear classification functions LCF1 (the absence of infectious complications) and LCF2 (the presence of infectious complications) are determined by formulas: LCF1=-12.2-1.29X1-0.27X2-0.87X3+4.75X4+3.13X5+10.68X6, LCF2=-8.78+0.74X1+0.93X2-0.15X3+3.78X4+ +2.77X5+7.6X6, wherein: X1 - burdened maternal obstetric and gynecological history (0 - no 1 - yes), X2 - mothers chronic nicotine intoxification (0 - no 1 - yes), X3 - cesarean section (0 - no 1 - yes), X4 - high eosinophil count as shown by infants complete blood count (0 - no 1 - yes), X5 - infants feces Escherichia count by real-time polymerase chain reaction (1 - insufficient 2 - normal 3 - increased), X6 - use of the probiotic form of E. faecium L3 in the integrated therapy of the premature infant (1 - no 2 - yes) the LCF1 and LCF2 are compared, and the success rate is predicted if observing LCF1>LCF2.EFFECT: using the declared method enables the more effective nursing of the premature infants, preventing the development of chronic diseases, reducing the number of unfavourable outcomes.2 exИзобретение относится к области медицины и предназначено для прогнозирования успешности профилактики инфекционных осложнений у недоношенных новорожденных детей в период выхаживания в условиях стационара. Недостатками известных способов является отсутствие данных об его использовании у недоношенных детей и, в том числе, в целях профилактики и невысокая степень точности. Предлагается прогнозирование успешности профила