Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid homeostasis in a subject having bile acid diarrhea or bile acid malabsorption

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专利权人:

发明人:

Lei Ling,Jian Luo

申请号：

US14985031

公开号：

US09878008B2

申请日:

2015.12.30

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and variants or fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as bile acid homeostasis modulating activity, and methods for and uses in treatment of bile acid and other disorders.

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中国工程科技知识中心

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