SOSTEK MARK,AULT BRIAN,ORLEMANS EVEARDUS,PLACHETKA JOHN R.
申请号：
TN2011000096
公开号：
TN2011000096A1
申请日:
2011.02.25
申请国别(地区):
TN
年份:
2012
代理人:
摘要：
The present disclosure is directed to the use of naproxen, or pharmaceutically acceptable salt thereof, and esomeprazole, or pharmaceutically acceptable salt thereof in the manufacture of a pharmaceutical composition in unit dose form, wherein said esomeprazole, or pharmaceutically acceptable salt thereof, is released from said unit dose form at a specified pH, wherein one unit dose form is for administration as an AM dose and a second unit dose form is for administration about 10 hours later as a PM dose to target a specified pharmacokinetic profile.
