After this invention, (A) the phosphatide and, (B) the electric charge substance and/or (C) includes features that mean particle diameter is 1 millimicrons or less the membrane strengthening substance as the constitution component, possesses the hardness which possesses cell membrane permeability, enclosing the medicine into the liposome, and the said liposome for rear eye arrival being the medicine composition for the eye disease, it arrives in the rear eye with instillation, at the same time after is not cell poisonous, using the liposome and the said liposome it offers the medicine composition for the eye disease.本発明は、(A)リン脂質と、(B)電荷物質及び/又は(C)膜強化物質とを構成成分として含み、細胞膜透過性を有する堅さを有し、平均粒子径が1μm以下であることを特徴とする、後眼部到達用リポソーム、並びに該リポソームに薬剤を封入した後眼部疾患用医薬組成物であって、点眼によっても後眼部に到達し、かつ細胞毒性も無い、リポソーム及び該リポソームを用いた後眼部疾患用医薬組成物を提供する。
