Subo Liao;Peter X. Wang;David W. Berberich;Douglas C. Miller
发明人:
Subo Liao,Peter X. Wang,David W. Berberich,Douglas C. Miller
申请号：
US13196921
公开号：
US08703949B2
申请日:
2011.08.03
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides processes for the preparation of N-alkyl morphinans without the isolation of nor-morphinan intermediates. In particular, the invention provides tandem hydrolysis/alkylation reactions for the synthesis of N-alkyl morphinans.
