您的位置: 首页 > 农业专利 > 详情页

КОМПОЗИЦИИ, УЛУЧШАЮЩИЕ ПЕРФУЗИЮ В ОБЛАСТИ ИНФАРКТА И СПОСОБЫ ВОССТАНОВЛЕНИЯ СОСУДИСТОГО ПОВРЕЖДЕНИЯ
专利权人:
ЭМОРСАЙТ; ИНК. (US)
发明人:
ПЕКОРА Эндрю (US),ПРЕТИ Роберт (US)
申请号:
RU2011127184/15
公开号:
RU2011127184A
申请日:
2009.12.02
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A method for the treatment or reduction of myocardial injury area of ​​the subject being revascularization after an acute myocardial infarction due to natural pathological process, wherein the method comprises the steps of: (a) parenterally administering to the subject through a catheter sterile pharmaceutical composition comprising: (i) improving perfusion infarct region number selected non-swelling sterile chemotactic product of hematopoietic stem cells as a first therapeutic agent, which improves erfuziyu in myocardial number chemotactic product of hematopoietic stem cells comprises enriched population of isolated autologous CD34 + hematopoietic stem cells comprising the subpopulation of highly CD34 + cells expressing CXCR-4 and having a CXCR-4-mediated chemotactic activity, which enriched population of isolated autologous CD34 + hematopoietic stem cells provides at least, 0,5 × 10vysokoaktivnyh CD34 + cells expressing CXCR-4 and having CXCR-4 mediated hemotak matic activity (ii) a stabilizing amount of serum, wherein a stabilizing amount of serum is more than 20% (.. v / v), and (iii) optionally a therapeutically effective amount of at least one compatible second therapeutic agent and (b) improve perfusion in at least one region of myocardial relative to control cases where at least 70% of the cells in the enriched population of selected CD34 + cells comprising the subpopulation of highly active cells, which express CXCR-4, and which have CXCR- 4
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充