This invention relates to quaternary ammonium compound for use as an inhibitor of protein kinase C alpha, of formula I:wherein:R1 is selected from the group of alkyl, alkene, aryl or alkylaryl group preferably R1 is a benzyl, alkylbenzyl or alkylphenyl group more preferably benzyl or methylphenyl group optionally substituted by hydroxyl, oxo, nitro, amido, carboxy, amino, cyano, alkoxy, alkyl, alkene, alkyne, ester or heteroalkyl group.R2 is an alkyl chain comprising at least 12 carbon atoms preferably comprising 14, 16 or 18 carbon atomsR3 or R4 are identical or different and each is selected from an alkyl chain preferably a C1-C4 alkyl chain more preferably is methyl group.X- is selected from an anion of a pharmaceutically acceptable acid or from halo group preferably X- is selected from halo group more preferably is Cl- or Br-. In particular, the present invention relates to a long-chain quaternary ammonium of formula (I) as a wound healing and/or an anti-inflammatory agent for use in the treatment of eye conditions.
