Jean Bennett,Junwei Sun,Kenneth Shindler,Devin McDougald
申请号:
US16607834
公开号:
US20200131532A1
申请日:
2018.04.24
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compositions and methods are provided for treating ocular neuropathy in a subject. In one aspect, a recombinant adeno-associated viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding NRF2. In another aspect, a recombinant adeno-associated viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding SIRT1. In desired embodiments, the subject is human, cat, dog, sheep, or non-human primate.