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Use of AMPK-activating imidazole derivatives, preparation process therefor and pharmaceutical compositions comprising them
专利权人:
Sophie Hallakou-Bozec;Christine Charon;Dominique Marais;Gerard Moinet
发明人:
Gerard Moinet,Dominique Marais,Sophie Hallakou-Bozec,Christine Charon
申请号:
US12373310
公开号:
US08329738B2
申请日:
2007.06.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to the use of imidazole derivatives of the formula (1):in which A, R′1, R′2 and R′3 are as defined in the description, as AMPK activators.The invention also relates to processes for the preparation of the said compounds, to their uses for the preparation of medicaments for the treatment of insulin resistance, diabetes and related pathologies, and also obesity, and to the pharmaceutical compositions comprising them.Certain compounds of the formula (1) are novel and, in this respect, also form part of the invention.
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