Provided is a composition effective for preventing onset and/or recurrence of stroke, in particular, which is expected to be effective for preventing onset and/or recurrence of stroke in a hyperlipidemia patient who has been treated with HMG-CoA RI, or in particular, recurrence of stroke in a patient who is beyond six months after the onset of stroke i.e., a composition for preventing onset and/or recurrence of stroke, containing ethyl icosapentate as its effective component.
